Yes, under the following conditions :
- your UpSlide version must be 4.3.1 or higher,
- all your files must be either PowerPoint presentations or Word documents, but not both.
Then, you simply have to click the Update all button.
By default, this feature lists all imported shapes in the active presentation or document.
But you can also select the "Include all opened documents" option to see all excel imports grouped by file (see picture below).
You can then update all of your excel imports in a single click.